ABSTRACT Asthma is an allergic airway disease characterized by distinct immune environments that can alter host responses to respiratory viral infections; however, its impact on coronavirus disease 2019 (COVID-19) severity remains unclear. To investigate how allergic airway inflammation affects severe acute respiratory...
Takao Iketani, N. Iwata-Yoshikawa, Yusuke Sakai et al.· Msphere· 0 citations
ABSTRACT In immunocompromised patients, persistent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection carries the risk of prolonged viral shedding and emergence of new variants. To reproduce the key features of persistent SARS-CoV-2 infection and evaluate its transmissibility, mouse-passaged SARS-Co...
Kaya Miyazaki, Nozomi Shiwa-Sudo, N. Iwata-Yoshikawa et al.· Microbiology spectrum· 0 citations
This review provides a comprehensive synthesis of tick-borne viral infections in East Asia, with particular emphasis on Japan, integrating pathological, virological, and clinical perspectives and underscores the importance of a synergistic One Health framework that incorporates both human and veterinary pathology to ad...
Overall, NIID-002 fulfills the key requirements for the pandemic preparedness of CVV, combining reduced pathogenicity, broad antigenic reactivity, and adequate production efficiency, which underscores the continued need for surveillance and refinement of influenza vaccine strategies to address evolving viral threats.
