Revisiting the Mechanism of Fluoroacetate Dehalogenase-Catalyzed Degradation of Fluorocarboxylic Acid via Cluster Models.
Fluoroacetate dehalogenase (FAcD) is a unique, nonmetal-dependent enzyme capable of cleaving the inert C-F bond of fluoroacetate (FA) under mild conditions, making it an important enzymatic model for organofluorine degradation. This study investigated the catalytic degradation mechanism of FA by FAcD using density func...