Author

Yuting Hu

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Open access Sep 2026

Listeriolysin O recruits UBA1 to ubiquitinate NLRP3 and suppress inflammasome defence

The NLRP3 inflammasome is a central cytosolic defence pathway against infection, yet intracellular pathogens must restrain this response to preserve their replicative niche. Here we identify a ubiquitin-dependent immune-evasion mechanism in which L. monocytogenes uses listeriolysin O (LLO) to destabilise NLRP3. The N-t...

Long-Wei Yuan, An Ding, Yu-Chao Feng et al. · bioRxiv · 0 citations

Open access Aug 2026

Joint trajectories of obesity and depressive symptoms and risk of incident glaucoma: a 16-year prospective cohort study from the Health and Retirement Study

Background Obesity and depression frequently co-occur in older adults and share pathways potentially relevant to glaucoma, yet their dynamic co-evolution and joint contribution to glaucoma risk remain poorly characterized. Objectives This study aimed to identify joint longitudinal trajectories of body mass index (BMI)...

XiaoDan Xu, Yuting Hu, Fuju Shi et al. · Frontiers in Aging Neuroscie... · 0 citations