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Yuting Lyu

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Preprint Jul 2026

Evidence-Grounded Mapping of Multimodal Human Sensing Psychological Transdiagnostic Dimensions

Mobile and wearable sensing enables longitudinal observation of behavior, yet translating these signals into meaningful mental health constructs remains difficult. We introduce a clinician-in-the-loop benchmark for evaluating whether large language models (LLMs) can generate evidence-grounded Brief Hierarchical Taxonomy of Psychopathology (B-HiTOP) item profiles from passive sensing, ecological momentary assessment (EMA), and questionnaire evidence. Using the Generalization of Longitudinal Behavior Modeling (GLOBEM) dataset, we construct 14,592 participant-day instances and align multimodal evidence to 29 B-HiTOP items across five spectra. Since GLOBEM lacks B-HiTOP responses, we evaluate evidence compatibility (C) rather than diagnostic accuracy, separating substantive predictions from abstentions when evidence is insufficient for item-level scoring. Two-stage prediction improves C for EMA and questionnaire evidence, but reduces C under passive sensing and combined evidence and produces more conservative score distributions across models, spectra, and evidence settings. Overall, semantic abstraction helps organize heterogeneous self-report evidence while becoming an information bottleneck for indirect behavioral sensing signals.

Xiyuan Hu, Xiang-Yuan Xue, Yuting Lyu et al. · 0 citations