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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Yuting Wang

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Open access Oct 2026

Structure-guided discovery of novel ERα-binding peptides with in vitro antiproliferative activity

Abstract Uterine leiomyoma (UL) is an oestrogen-dependent tumour, and ERα is closely associated with abnormal proliferation of UL cells. This study used structure-guided virtual screening of a 59,319-member peptide library, followed by molecular docking, MST, MD simulation, MM/PBSA analysis, MTT assays, ERα knockdown,...

Ting Guo, Yan Zhang, Shu-Dan Yang et al. · 0 citations

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