Open access
Aug 2026
Creation and characterization of novel knock-in mouse models of hypophosphatasia
These knock-in mouse models recapitulate genotype-dependent dental manifestations of HPP and indicate that dental phenotypes are influenced not only by circulating TNAP levels but also by the functional effects of individual ALPL variants.
R. Okawa, Marin Ochiai, H. Kurosaka et al.
· JBMR Plus · 0 citations