ROS-Scavenging Single-Component Polymeric Nanocarriers for Precision siRNA Delivery in Pulmonary Fibrosis Therapy.
Idiopathic pulmonary fibrosis (IPF) is a progressive refractory lung disorder with limited effective therapies. Although RNA interference (RNAi) holds promise for IPF treatment, current delivery systems are hampered by complex preparation, redundant components, and an inability to modulate oxidative stress, which sever...