Open access
Jul 2026
In Situ Programmable Modulation of Hydrogel Stiffness for Stage‐Adaptive Bone Regeneration
A dynamic stiffness hydrogel system designed to mimic the stiffness variation of the ECM during bone repair, based on a 3D interpenetrating polymer network, that exhibited the ability to repair critical‐sized bone defects, underscoring its therapeutic potential.
Yuxin Yang, Fan Yang, Lu Wang et al.
· Advancement of science · 0 citations