Open access
Aug 2026
From low- to high-level resistance: dynamic transcriptional adaptations and efflux pump amplification in cefiderocol-stressed Pseudomonas aeruginosa
Pseudomonas aeruginosa is a bacterium with high antimicrobial resistance to several drugs including carbapenems. Recently, resistance to cefiderocol (FDC), a new siderophore cephalosporin, has been reported despite its rare use in clinical practice. Therefore, this study aimed to investigate the dynamics of different r...
Ting Zhang, Han-Xu Hong, Jun Wang et al.
· Frontiers in Microbiology · 0 citations