Yuxuan Xiong

Heart rate fragmentation in psychiatry: across age stages and association with conventional heart rate variability.

Its robust inverse association with conventional HRV, particularly HF, suggests partial overlap with traditional HRV and supports fragmentation as a complementary marker of beat-to-beat rhythm organization.

Dynamic, differentiated clinical trajectories and prediction in clinical high risk for psychosis.

Neddylation-dependent CUL3-KLHL12 E3 ligase drives microglial oxidative stress and neuroinflammation in traumatic brain injury by targeting GCLM for degradation.

The findings characterize the Neddylation-CUL3-KLHL12-GCLM axis as a critical regulator of microglial redox homeostasis and highlight this pathway as a promising therapeutic target for TBI intervention.