Author

Yuyang Zhou

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Review Open access Jul 2026

Antimicrobial peptides in anti-infective and immunomodulatory applications: Mechanisms, challenges, and emerging computational design.

This review examines how the diverse molecular mechanisms through which AMPs exert antimicrobial effects-including membrane disruption, intracellular targeting, and immunomodulation-are intrinsically linked to their structural diversity and ecological breadth and critically evaluates engineering strategies that improve developability.

Yan-Lin Wang, Ya-Qian Yang, Yuyang Zhou et al. · Zoological Research · 0 citations

Jul 2026

A Scalable Pan-Genomic Pipeline for Annotation-Free Discovery of Species-Specific Markers: Application to Staphylococcus aureus

An open-source, annotation-independent pan-genomic pipeline featuring an overlapping sliding-window algorithm and a three-tier subtractive screening funnel successfully circumvents conventional gene-centric limitations, providing a generalizable computational strategy for target discovery across other high-priority bacterial pathogens.

Yuyang Zhou, Jiayi Wang, Junhua Xiao et al. · Journal of Bioinformatics an... · 0 citations