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Author

Z. Armstrong

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Open access Jul 2026

Identification of cellular intermediates unveils unique enzymes for flagellar glycan biosynthesis in Clostridioides difficile.

This study chemically synthesized two hitherto undescribed biosynthetic intermediates that were predicted based on bioinformatic analyses, CDP-threonine and CDP-N-methylthreonine, and showed that they are involved in the Type A PGM biosynthesis, as evidenced by mass spectrometric analyses of extracts of a set of C. dif...

P. Hensbergen, Bob van Puffelen, Nina Musch et al. · 0 citations
Open access Jul 2026

The development of activity-based mannanase probes

The synthesis of cyclophellitol-inspired ABPs based on mannobiose, mannotriose, and glucomannose are described and their use in reporting mannanase activities in secretomes from saprophytic bacteria and fungi grown on mannan-containing biomass polysaccharides is described.

Massimo Tedeschi, Vincent A. J. Lit, Nicholas G. S. McGregor et al. · 1 citation

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