Author

Z. Fan

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Open access Sep 2026

Engineering Klebsiella oxytoca for enhanced 2,3-butanediol production from gluconate

Historically, microbial production of 2,3-BD has relied predominantly on glucose as the substrate. However, its fermentation necessitates microaerobic conditions due to inherent redox imbalances. This limitation complicates process control and can lead to undesirable late-stage consumption of 2,3-BD. This study...

Martin Jeffers, Takao Kasuga, Zhi-Liang Fan · Microbial Cell Factories · 0 citations

Open access Sep 2026

Integrated hydrothermal and microbial valorization of almond shells into xylooligosaccharides and cellobionic acid

Almond shells are abundant lignocellulosic by-products with great potential for sustainable valorization. This study developed an integrated biorefinery process to produce xylooligosaccharides (XOS) and cellobionic acid (CBA) through hydrothermal pretreatment and fungal simultaneous saccharification and fermentation. P...

Sumi Sharma, Hamidreza Shapouri, Shirin Kazemzadeh Pournaki et al. · Bioresources and Bioprocessi... · 0 citations

Open access Sep 2026

Engineering Thermothelomyces heterothallica for cellobionate production

In this study, a thermophilic cellulolytic filamentous fungus Thermothelomyces heterothallica was engineered for direct production of cellobionic acid (CBA) from alkali-pretreated wheat straw without the addition of external cellulases. The CBA bioproduction pathway was established through sequential disruption of gene...

Bakht Zada, Hamidreza Shapouri, Jia-Jie Wang et al. · Bioresources and Bioprocessi... · 0 citations