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Open access Aug 2026

Associations Between Cerebral Amyloid Angiopathy, Cognitive Impairment, and Depressive Symptoms

Background and Objectives Cerebral amyloid angiopathy (CAA) is associated with intracerebral hemorrhage, cognitive decline, and dementia. We examined (1) associations between CAA, cognitive impairment, and depressive symptoms; (2) whether depressive symptoms mediate the relationship between CAA and cognition; and (3) w...

Nikita Nukala, Ryan T. Muir, Andrew E. Beaudin et al. · 0 citations
Open access Jul 2026

Associations among mild behavioral impairment, cognition, and brain pathology in preclinical autosomal dominant Alzheimer's disease

Abstract INTRODUCTION The Mild Behavioral Impairment Checklist (MBI‐C) captures neuropsychiatric symptoms in individuals at risk of dementia. In this study, we examined MBI‐C scores in autosomal dominant Alzheimer's disease (ADAD). METHODS We included 83 cognitively unimpaired presenilin‐1 E280A mutation carriers and 1...

Catarina Tristão-Pereira, D. Vásquez, Jorge Alcina et al. · 0 citations

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