Incorrect inhalation technique is one of the main causes of ineffective inhaled therapy in patients with chronic obstructive pulmonary disease (COPD), leading to increased frequency of exacerbations and hospitalizations. Measuring peak inspiratory flow (PIF) and determining its optimal values for a specific dry powder...
N. Trushenko, B. Lavginova, G. N. Nekludova et al.· PULMONOLOGIYA· 0 citations
Triple CFTR modulator therapy with ivacaftor + tezacaftor + elexacaftor and ivacaftor (ITE) has substantially changed the clinical course and prognosis of cystic fibrosis. The expanding use of the bioequivalent generic Trilexa® highlights the need to summarize evidence on its clinical efficacy and safety, including out...
Z. Merzhoeva, I. Levina, B. Lavginova et al.· PULMONOLOGIYA· 0 citations
Background. Late-onset asthma (after 40 years) is characterized by more severe disease, frequent exacerbations, fixed bronchial obstruction, and high comorbidity; prognostic tools for this age group, including risk models for rehospitalization and mucus plugs, remain insufficiently developed.
Aim. To develop and valid...
T. U. Bogatyreva, V. Gaynitdinova, E. S. Aynetdinova et al.· Consilium Medicum· 0 citations
Background. Cystic fibrosis (CF) is a multisystem disease in which liver involvement occurs in 20-40% of patients. The introduction of CFTR modulator therapy has substantially improved the prognosis of patients with CF; however, patients with established cirrhosis have typically been excluded from clinical trials, whic...
Z. Merzhoeva, O. Suvorova, I. A. Levina et al.· Lechaschi Vrach· 0 citations
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