Author

Z. Mesrizadeh

2 papers indexed here

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Open access Sep 2026

Differential peripheral immune dynamics underlie therapeutic response to chemotherapy and chemoimmunotherapy in triple-negative breast cancer

Abstract Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype with limited treatment options and response to immune checkpoint inhibitors. Tumor-infiltrating lymphocytes have been extensively studied; however, the integration of peripheral immune dynamics with mechanistic regulation underlying th...

Z. Mesrizadeh, Kavitha Mukund, Shankar Subramaniam · ImmunoHorizons · 0 citations

Open access Oct 2026

Spatial context of cellular heterogeneity in triple-negative breast cancer reveals actionable subtypes

This study identified three reproducible TNBC ecosystem subtypes that encode distinct spatial tumor-microenvironment architectures and clinically relevant treatment-response phenotype that provide the basis for subtyping and candidate therapeutic vulnerabilities.

Z. Mesrizadeh, Kavitha Mukund, Li-Xin Yang et al. · bioRxiv · 0 citations