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Open access Sep 2026

460. HMGB1 contributes to blood-brain barrier disruption and neuronal injury in stress-induced depression

Abstract Background Depression is a complex neuropsychiatric disorder, with inflammation and blood-brain barrier (BBB) dysfunction contributing significantly to its pathogenesis. High Mobility Group Box 1 (HMGB1), has been implicated in various inflammatory processes and neurological disorders. However, its role in dep...

Z. Qi, L. Kuang · 0 citations

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