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Open access Jul 2026

Investigation of PDCD1 Gene Polymorphisms and Haplotypes in COVID‐19 Severity and Outcome in a Brazilian Population

COVID‐19 severity and survival are influenced by the host immune response to SARS‐CoV‐2. Programmed cell death 1 (PD‐1), a key immune checkpoint, regulates T‐cell activation and antiviral immune balance. Since genetic variability can modulate these responses, we investigated whether the PDCD1 polymorphisms rs11568821 C...

S. L. Moretto, Pedro Luis Candido de Souza Cassela, G. L. Trigo et al. · 0 citations

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