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Z. Yu

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Open access Oct 2026

Rare variant burden complements polygenic risk in breast cancer and is associated with earlier diagnosis

Breast cancer affects approximately one in eight US women during their lifetime, and about 10% of new cases occur before age 45. Polygenic risk scores (PRS) are associated with breast cancer risk, and previous studies have evaluated PRS alongside pathogenic-variant carrier status. Whether a continuous, gene-effect-weig...

Z. Yu, Y. Dong · 0 citations
Open access Sep 2026

Joint effects of air pollution and temperature on glycemia: An exposome analysis in European cohorts.

BACKGROUND The interdependent long-term effects of a climate-change relevant residential exposome on glycemia in persons without diabetes are not well understood. Applying the exposome analysis approach that we previously developed for lung function, the current analysis aims to identify exposome factors including thei...

A. Jeong, J. Edstorp, G. Lovison et al. · 0 citations
Open access Jul 2026

Electrocardiogram-Based Deep Learning for Time-Resolved Prediction of Heart Failure With Reduced Ejection Fraction: A Multinational Study

This ECG-based deep learning survival model provides individualized, time-resolved, and clinically interpretable estimates of future HFrEF risk with robust performance across multinational cohorts and supports the potential of AI-enabled ECG analysis as an accessible tool for early HFrEF risk stratification within rout...

L. Pan, S. Li, J. Huo et al. · 0 citations

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