Zachary L. Klamer

Abstract A033: Gangliosides as regulators of the hybrid epithelial-mesenchymal phenotype in pancreatic ductal adenocarcinoma

Investigating whether hybrid cancer cells have distinct metabolic, transcriptional, and cell-surface glycan and protein profiles that enable the definition of such cells in primary tumors and in-vitro systems found that cells undergoing EMT increase glycolysis, increase glucose commitment to sialic acid and glycosphing...