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Zaixing Yang

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Open access Oct 2026

Multi-omics analysis reveals coordinated transcriptional and epigenetic remodeling of tenocytes under IL-1β-driven inflammatory stimulation

Tendinopathy is frequently associated with chronic inflammation driven by pro-inflammatory cytokines. Among these, interleukin-1β (IL-1β) serves as a central mediator of tendon degradation, yet its genome-scale transcriptional and epigenetic consequences in tenocytes remain incompletely characterized. We pro...

Wen-Yan Zhou, Xiao-Nan Wang, Jun-Xin Lin et al. · 0 citations
Open access Aug 2026

Colitis Ameliorates Murine Autoimmune Cholangitis Through Polarization of M2 Macrophages and Inhibition of CD8+ T-Cells

Background/Aim: Primary biliary cholangitis (PBC) is a form of chronic autoimmune cholangitis of enigmatic etiology and pathogenesis. While numerous studies indicate an association between inflammatory bowel disease (IBD) and PBC, the bidirectional impact on disease progression remains unclear. This study investigated...

Miao He, Hao-Qing Liu, Miaomiao Zhang et al. · 0 citations

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