Clinical and Genetic Characterization of Two Siblings with SCN9A- Related Congenital Insensitivity to Pain Type 1: Two Case Reports
Congenital insensitivity to pain (CIP) is an extremely rare syndrome with various clinical features, characterized by a dramatic impairment of pain perception since birth. Although many genes are known to cause this condition, SCN9A -related disease remains underrecognized, and affected individuals cannot perceive...