Malnourished children are susceptible to an increased risk of mortality owing to impaired immune functions. However, the underlying mechanism of altered immune functions and its interaction with malnutrition is poorly understood. This study investigates the immune function and evaluates the effect of a particular nutri...
Zannatun Noor, M. Hasan, Md. Amran Gazi et al.· Scandinavian Journal of Immu...· 6 citations
Background and objective Serological screening with a confirmation through biopsy has improved the understanding of coeliac disease (CD) epidemiology worldwide. Prevalence of CD in Bangladesh is not yet explored and therefore, we aimed to assess the seroprevalence of CD in slum-dwelling malnourished children and adults...
Md. Amran Gazi, Subhasish Das, M. Mahfuz et al.· BMJ Open Gastroenterology· 4 citations
Abstract. Chronic exposure to infectious agents results in environmental enteric dysfunction—a significant contributor to childhood stunting. Low plasma tryptophan (TRP), increased kynurenine (KYN), and KYN–TRP (KT) ratio are associated with infections and chronic immune activation. We postulated that both these condit...
Md. Amran Gazi, Subhasish Das, M. A. Siddique et al.· American Journal of Tropical...· 26 citations· ⚡1
The prevalence of norovirus infections in different geographical locations and their attribution to childhood diarrhea is well established. However, there are no reports showing possible relationships of different norovirus genogroups with subsequent childhood malnutrition. In this study, we attempted to establish a po...
P. Palit, R. Das, Md Ahshanul Haque et al.· Viruses· 15 citations· ⚡1
Dysregulations in the mammalian target of rapamycin (mTOR) pathway are associated with several human anomalies. We aimed to elucidate possible implications for potential aberrations in the mTOR pathway with childhood malnutrition. We analyzed the activity of phospho-mTORC1 and the expressions of several mTOR pathway ge...
P. Palit, Md. Amran Gazi, Subhasish Das et al.· Nutrients· 5 citations
Children suffering from severe acute malnutrition (SAM) have a weakened immune system. The relationship between malnutrition and alterations in the frequency of peripheral blood mononuclear cells (PBMCs) remains unclear. This study investigated the altered immune responses in Bangladeshi children with SAM compared to h...
Zannatun Noor, S. Islam, M. Hasan et al.· Immunobiology· 3 citations
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