Author

Zechen Wang

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Review Open access Oct 2026

Immune‐Cell Dynamics in the Tumor Microenvironment: Implications for Cancer Therapy

ABSTRACT Immune‐cell dynamics within the tumor microenvironment (TME) determine whether immune cells can reach, recognize, and sustain antitumor function against malignant cells under suppressive pressure. These dynamics are shaped by hypoxia, nutrient stress, cytokine and chemokine signaling, stromal architecture, vas...

Pin Guo, Yi-Zhao Xie, R. Song et al. · MedComm · 0 citations

Jun 2026

Targeting TAK1 to overcome cisplatin resistance in lung adenocarcinoma by rewiring the NF-κB and p53 signaling.

TAK1 is established as a key hub in cisplatin resistance and 5Z7 reverses resistance by targeting TAK1 to coordinately regulate NF-κB/p53 signaling, providing a foundation for potential clinical translation.

Wenyan Lu, Kunhao Tang, Zechen Wang et al. · Biochemical Pharmacology · 0 citations