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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Ze-Hong Lin

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Open access Aug 2026

Unraveling the pathogenic mechanisms of osteoarthritis and obesity: An integration of GWAS, cellular specificity, and spatial transcriptomics

This study precisely anchors the genetic risk of OA and obesity to specific brain regions, cell types, and developmental time windows, providing a novel perspective for understanding the pathological mechanisms of OA.

Ze-Hong Lin, Ji-Hui Wei, Hong-Hai Zhou · 0 citations
Open access Aug 2026

A New Recruitable E3 Ligase UHRF1 Supporting Targeted Protein Degradation: A Minimal Azide as a Recruitment Ligand

The first small-molecule GPX4 degraders that incorporate either electrophilic warheads or a minimal azide group as an E3 recruitment ligand are reported, thereby expanding the E3 ligase toolbox and offering a promising strategy for targeted cancer therapy.

Ze-Hong Lin, Kang Duan, Rui Wan et al. · 0 citations

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