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Integrated Transcriptomic Analysis Identifies a Candidate INHBA/Activin A-Associated Macrophage–MuSC Communication Axis in Human Skeletal Muscle Ageing
Skeletal muscle ageing is accompanied by impaired regeneration and remodelling of the multicellular niche, yet how age-related immune changes relate to altered muscle stem cell (MuSC) states in humans remains unclear. Here, we integrated bulk RNA-sequencing, scRNA-seq and an independent older adult cohort analysis to c...