Background Routine platelet indices have been linked to blood pressure and vascular risk. However, longitudinal evidence on the association between platelet count (PLT), mean platelet volume (MPV), plateletcrit (PCT), and platelet distribution width (PDW) and incident hypertension remains limited, and it is unclear whe...
Ze-Kai Chen, Zhen He, Sha-Sha Zhou et al.· Journal of Global Health· 0 citations
Aims Metabolic dysfunction, inflammation, and lipoprotein(a) [Lp(a)] reflect different biomarker domains associated with atherosclerotic cardiovascular disease (ASCVD) risk. We examined the individual and joint associations of the triglyceride–glucose (TyG) index, high-sensitivity C-reactive protein (hs-CRP), and Lp(a)...
Guan-Lin Chen, Yu-Long Lan, Dan Wu et al.· Frontiers in Endocrinology· 0 citations
Heart failure (HF) causes a heavy disease burden globally. Identifying etiological risk factors is essential for informing disease prevention and developing new treatment strategies. This review synthesizes insights from published Mendelian randomization (MR) studies on risk factors associated with HF. MR analyses supp...