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Author

Ze-Yu Zhang

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Review Open access Sep 2026

AAV-mediated gene therapy for Alzheimer’s disease: neuroprotective mechanisms and translational challenges

The biological basis for adeno-associated virus delivery in the central nervous system is summarized and major therapeutic strategies for Alzheimer’s disease are discussed, including approaches targeting Aβ production and clearance, tau expression and degradation, immune microenvironment remodeling, apolipoprotein E mo...

Ze-Hua Yu, Yang Li, Ze-Yu Zhang et al. · 0 citations

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