Open access
Sep 2026
Median effective dose of fospropofol disodium for suppression of the cough reflex during tracheostomy tube exchange in patients with disorders of consciousness receiving fixed-dose sufentanil
The suppressive effect was dose-dependent; however, higher doses were associated with increased risks of hypotension and apnea, indicating the need for individualized dose titration.
Chao-Feng Chen, Li-Jun Wu, Xin-Xin Yue et al.
· Frontiers in Pharmacology · 0 citations