Author

Zechen Wang

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Jun 2026

Targeting TAK1 to overcome cisplatin resistance in lung adenocarcinoma by rewiring the NF-κB and p53 signaling.

TAK1 is established as a key hub in cisplatin resistance and 5Z7 reverses resistance by targeting TAK1 to coordinately regulate NF-κB/p53 signaling, providing a foundation for potential clinical translation.

Wenyan Lu, Kunhao Tang, Zechen Wang et al. · Biochemical Pharmacology · 0 citations