Novel Nabumetone-Chalcone-Based Pyridine Hybrids: Synthesis, Characterization, and Cytotoxic Activity against the A549 Lung Cancer Cell Line and Normal Human Dermal Fibroblasts (HDFn)
Background: Non-small cell lung cancer (NSCLC) is the leading cause of cancer mortality, necessitating the continuous discovery of targeted therapies. Aim of the Study: This study aimed to synthesize and characterize six novel nabumetone-derived heterocyclic compounds (4-9) by integrating chalcone derivatives with pyri...