Author

Zeinab A. El-Gendy

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Aug 2026

Alogliptin mitigates doxorubicin-induced cardiotoxicity in rats: Implications of SIRT3/NRF2 pathway and miRNA-133a.

Present results proved the prophylactic ALO antioxidant, anti-inflammatory, anti-apoptotic, and anti-fibrotic influence on the DOX-induced cardiotoxicity with proposed mechanisms entailing the activation of SIRT3 pathway that may be governed by miRNA-133a.

N. F. Elmongy, Mohamed Ali Abbas, S. Elshora et al. · Tissue & Cell · 0 citations

Open access Aug 2026

Guazuma ulmifolia butanol extract protects against cadmium-induced hepatotoxicity via HO-1/Sirt-1 activation, miRNA–lncRNA modulation, and metabolic reprogramming

Gul-BuOH affords dose-dependent protection against Cd-induced liver injury by modulating oxidative stress, inflammation, metal detoxification, and metabolic pathways, supporting the traditional use of G. ulmifolia and its potential as a multi-target hepatoprotective agent.

O. A. Elsabagh, Abdelbaset M. Elgamal, Heba A. Hassan et al. · PLoS ONE · 0 citations

Open access Jan 2026

Protective Role of Linagliptin in Cisplatin‐Mediated Liver Injury: Involvement of STAT3 and AMPK/SIRT1/PGC‐1alpha Mitochondrial Energy Sensing Networks

The results indicate that Lina protects against Cis‐induced liver damage by leveraging its antioxidant, anti‐inflammatory, and metabolic regulation properties.

M. A. Elbaset, Bassim M S A Mohamed, Passant E. Moustafa et al. · Advances in pharmacological... · 0 citations