Sep 2026
EGFR kinase inhibitors from novel thiazole derivatives: synthesis, anticolon cancer, docking, and ADME studies.
Compound 4j represents a promising lead candidate for the development of novel EGFR-targeted anticancer agents and demonstrated remarkable potency with an IC50 value of 0.27 µM.
Amani M. R. Alsaedi, Alaa M. Abu Alnjaa, Amel S. Younes et al.
· Future Medicinal Chemistry · 0 citations