Effects of PPAR Modulation on Cognitive Function and Oxidative Stress in Experimental Alzheimer's Disease: A Systematic Review and Meta-analysis.
Oxidative stress is a key pathological feature of Alzheimer's disease (AD), characterized by increased levels of reactive oxygen species (ROS), malondialdehyde (MDA), 4-hydroxynonenal, and protein carbonyls, alongside impaired antioxidant defenses such as superoxide dismutase (SOD). These alterations contribute to endo...