Enhanced renoprotective effects of remote ischemic postconditioning and alpha-lipoic acid via modulation of TLR4/MyD88/NF-κB and Nrf2/HO-1 pathways in renal ischemia-reperfusion injury.
This study aimed to evaluate the renoprotective benefits of remote ischemic postconditioning (RIPostC) and alpha-lipoic acid)ALA( against acute kidney injury (AKI) secondary to ischemia-reperfusion, focusing on the role of the TLR4/MyD88/NF-κB signaling cascade and the involvement of Nrf2 and HO-1. Individual and combi...