Zeng-Cai V. Guo

Large-Field Mesoscopic Spinning-Disk Confocal Microscopy Enhances Quantitative Fidelity for In Vivo Cerebrovascular and Calcium Sensing.

Reliable spatiotemporal quantification of fluorescent reporter signals in thick biological specimens remains a central challenge for analytical imaging, because out-of-focus background fluorescence in conventional single-photon wide-field microscopy degrades contrast, obscures signal identification, and compromises mea...