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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Zeng-Yu Zhang

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2 papers indexed here

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Sep 2026

Microglial P2Y12 Drives Chronic Cerebral Hypoperfusion via Ca2+ Activity-Mediated Neuroinflammation and Vascular Injury.

BACKGROUND Chronic cerebral hypoperfusion is a major driver of vascular cognitive impairment (VCI), but the role of microglial purinergic signaling in chronic cerebral hypoperfusion-induced neurovascular dysfunction remains undefined. This hypothesis-testing study with a novel research premise aimed to address this kno...

Qian-Qian Chen, Shi-Hao Yuan, Ya-Na Wang et al. · 0 citations
Open access Sep 2026

ZBP1‐mediated Treg cell dysfunction exacerbates neuroimmune dysregulation in Alzheimer's disease under metabolic stress

Abstract INTRODUCTION Metabolic stress increases Alzheimer's disease (AD) risk, but mechanisms linking metabolic dysfunction to neuroimmune dysregulation remain unclear. METHODS We assessed cognition in community‐dwelling participants and used high‐fat diet (HFD)‐fed 5xFAD mice, high glucose and high palmitate (HGHP)‐t...

Shan-Shan Huang, Zeng-Yu Zhang, Jia-Jie Xia et al. · 0 citations

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