B3GNT3 defines a spatially restricted dysfunctional T-cell niche and predicts immunotherapeutic outcomes in lung adenocarcinoma
Immunotherapy response in lung adenocarcinoma (LUAD) remains highly heterogeneous, underscoring the need for biologically informative markers of tumor immune dysregulation. B3GNT3, a glycosyltransferase implicated in several malignancies, is poorly characterized in LUAD with respect to the tumor immune microenvir...