Zhan-Li Shi

Network-guided computational prioritization of gut microbiota-associated metabolites in sepsis-associated intestinal injury.

Sepsis-associated intestinal injury involves barrier dysfunction and altered microbial metabolism, but microbiota-associated metabolites have not been systematically prioritized. We integrated curated microbe-metabolite and host-gene records, ligand-based target prediction, disease-gene databases, protein-protein inter...