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Open access Oct 2026

A Dual‐Delivery System Designed to Overcome EV‐Mediated Ferroptosis Resistance for Efficient Solid Tumor Therapy

ABSTRACT Tumor‐derived extracellular vesicles (EVs) are emerging as critical mediators of metabolic adaptation, yet their role in orchestrating ferroptosis resistance within the tumor microenvironment remains poorly understood. Here, we show that highly malignant osteosarcoma (OS) cells respond to ferroptotic stress by...

Ye-Chao Shen, Zhen-Guo Cao, Ze-Nan Wang et al. · 0 citations
Review Sep 2026

Prevalence and Clinical Implications of Vitamin D Deficiency in Spine Surgery Patients: A Large-Scale Clinical Study.

STUDY DESIGN Retrospective study. OBJECTIVE To determine the prevalence of vitamin D deficiency in patients undergoing spine surgery and to evaluate its distribution across demographic characteristics, bone mineral density (BMD), and spine disease categories. A secondary objective was to examine the associations betw...

Guo-Ping Xu, Huan-Ting Hu, Li-Hong Lai et al. · 0 citations

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