Targeting glymphatic-associated pathways for Alzheimer’s disease: a review of non-invasive modulation strategies, mechanisms, and emerging evidence
The glymphatic system, a cerebral waste clearance pathway identified over a decade ago, has reshaped understanding of Alzheimer’s disease (AD) pathogenesis by linking impaired brain homeostasis to amyloid-β and tau accumulation. This review synthesizes the biological mechanisms governing glymphatic function, including...