Efficacy and safety of negative-pressure nasal irrigation in pediatric chronic rhinosinusitis: A retrospective cohort study.
BACKGROUND Pediatric chronic rhinosinusitis (CRS) affects 6.37% of Chinese children. Negative-pressure nasal irrigation (NNPI) is recommended by Chinese guidelines, but international evidence remains limited. OBJECTIVE To evaluate efficacy and safety of NNPI combined with standard medical therapy in pediatric CRS....