Open access
Sep 2026
Characterization of METTL3/14-mediated m6A modification in human transcriptome using Nanopore direct RNA sequencing
Post-transcriptional RNA modifications modulate diverse aspects of RNA metabolism. N6-methyladenosine (m6A), one of the most abundant internal RNA modifications, is deposited by the core methyltransferase complex, METTL3 and METTL14. Oxford Nanopore Technologies (ONT) platform permits direct, single RNA molecule sequen...
Emily Kurtyan, Andrew J. Stein, Kelly J. Abdalla et al.
· PLoS Genetics · 0 citations