USP22 Enhances Mitochondrial Biogenesis via Stabilizing MYBBP1A in Non-Small Cell Lung Cancer.
This work reports the novel finding that ubiquitin-specific protease 22 (USP22), a key regulator of protein ubiquitination and transcriptional activity, regulates mitochondrial protein expression and oxidative phosphorylation and demonstrates that USP22 directly binds to MYB-binding protein 1A (MYBBP1A), thereby modula...