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Zhao Dai

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Open access Oct 2026

A system pharmacology framework to explore the therapeutic mechanism of Bushen-Yizhi formula against Alzheimer’s disease via integrating UPLC-Q-TOF-MS/MS, network analysis, machine learning and experimental validation

Alzheimer’s disease (AD) is an incurable neurodegenerative disease, and Bushen-Yizhi formula (BSYZ) has shown clinical potential for AD treatment, yet its bioactive components and pharmacological mechanisms remain unproven. To explore the therapeutic mechanism of BSYZ against AD-like cognitive impairment, a syste...

Jie-Qi Zhang, Hui-Juan Rao, Xiao-Lian Zhang et al. · 0 citations

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