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Author

Zhaodong Fei

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Open access Oct 2026

Integrated Serum and Spatial Metabolomics Reveals Compartmentalized Metabolic Reprogramming and Ferroptosis Susceptibility in Nasopharyngeal Carcinoma

Background: Nasopharyngeal carcinoma (NPC) is a malignancy highly prevalent in southern China. Metabolic reprogramming is a hallmark of cancer, yet the interplay between the systemic and local metabolic landscapes of NPC remains poorly characterized. This study aimed to identify serum metabolic biomarkers and character...

Hui-Ling Hong, Yu-Song Zhang, Ling-Hui Yan et al. · 0 citations
Open access Feb 2026

P-MES: Explainable pathology-based distant metastasis risk stratification in locally advanced nasopharyngeal carcinoma

A deep learning model based on whole slide images (WSIs) to predict post-treatment DM risk in patients with locally advanced NPC is developed and validated, demonstrating substantial discrimination, calibration, and clinical net benefit.

Liuling Wang, Jia-Xing Lin, Mengting Xu et al. · 0 citations

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