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Author

Zhao-Jie Chai

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Aug 2026

Quantifying the Biophysical Properties of Red Blood Cells in Gaucher Disease

Gaucher disease (GD), the most common lysosomal storage disorder, alters red blood cell (RBC) mechanics and circulation, contributing to vascular occlusions, bone infarcts, and splenomegaly. However, the individual roles of GD-RBC biophysical properties in these processes remain unclear. Here, we present a combined com...

Zhao-Jie Chai, M. de Person, Pierre A. Buffet et al. · 1 citation

GRAFT-ATHENA: Self-Improving Agentic Teams for Autonomous Discovery and Evolutionary Numerical Algorithms

This work proposes a certified regularization for ill-posed in vivo brain-flow reconstruction, developed a spectrally convergent physics-informed architecture, and established machine-checked universal-approximation theorems for two widely used architectures.

Juan Diego Toscano, Zhao-Jie Chai, G. Karniadakis · 10 citations

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