Engineered Vascularization: Neurovascular Niche Remodeling Enables Biomimetic Brain Organoids for Central Nervous System Research
Preclinical central nervous system (CNS) disease models face a persistent translational gap arising from interspecies differences and limited representation of the human neurovascular microenvironment. Human induced pluripotent stem cell-derived brain organoids provide a human-relevant platform for modeling brain dev...