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Author

Zhao-Xia Wang

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Open access Sep 2026

Complement C5 inhibitor as a rescue therapy for acute NMOSD attacks: a multicenter retrospective cohort study in China

Background Complement activation plays a key role in the pathogenesis of neuromyelitis optica spectrum disorder (NMOSD). While eculizumab effectively prevents relapses, its role in acute attacks remains uncertain. Methods We retrospectively analyzed 38 patients with acute NMOSD treated with eculizumab across seven tert...

Tao Wu, De-Cai Tian, De-Hui Huang et al. · 0 citations
Aug 2026

Neural stem cell-derived small extracellular vesicles ameliorate disease progression in the SOD1 G93A murine model of amyotrophic lateral sclerosis.

It is found that repeated administration of neural stem cell-derived extracellular vesicles (NSC-derived EVs) improved motor performance and provided protection to lumbar motor neurons, the neuromuscular junctions, and muscle morphology in the SOD1 G93A transgenic mouse model of ALS.

Y.S. Wan, Chao Gao, Jieyu Li et al. · 0 citations

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