Comparative evaluation of three protein nanoscaffolds for IHNV G ectodomain display in rainbow trout (Oncorhynchus mykiss).
Infectious hematopoietic necrosis virus (IHNV) causes severe losses in rainbow trout (Oncorhynchus mykiss) aquaculture. Vaccination is a critical control strategy, and the surface glycoprotein (G) is the primary target for protective immunity. However, recombinant G protein alone is poorly immunogenic, prompting the us...